As an independent research organization, the Morgridge Institute for Research explores uncharted scientific territory to discover tomorrow’s cures. In affiliation with the University of Wisconsin-Madison, we support researchers who take a fearless approach to advancing human health in emerging fields such as regenerative biology, metabolism, virology and medical engineering. Through public programming, we work to inspire scientific curiosity in everyday life.
The Morgridge Institute for Research seeks a highly motivated individual to fulfill the role of Research Specialist/Technician in the newly established Cantor Laboratory within its growing Metabolism Theme. The Cantor lab studies cellular metabolism and how it is influenced by environmental factors, with a particular focus on hematological cancers and normal lymphocytes. We apply a highly interdisciplinary approach that combines principles from biochemistry, engineering, and molecular biology with cutting-edge technologies in metabolomics, functional genomics (CRISPR), and chemical genetics. The successful candidate will have both a strong analytical background and an interest in the research scope described above, and will be responsible for learning, carrying out, and ultimately assisting in the instruction of various experimental protocols to fellow team members. The successful candidate will also assist in several other non-experimental tasks as highlighted below.
Primary responsibilities will include:
- Acquire high-level proficiency in a variety of experimental methods and techniques including, but not limited to:
- Basic molecular biology
- Bacterial culture
- DNA/RNA isolation
- Protein purification, Immunoblotting, and Protein-based assays
- Preparation of standard buffers and stock solutions
- Mammalian cell culture
- Employ sterile technique in the basic handling of reagents and human cells
- Preparation of complex media formulations
- Lentivirus production and infection
- Preparation of cultures for FACS-based single cell sorting
- Preparation of biological samples for metabolite profiling
- Basic understanding of LC/MS operation
- Data acquisition and analysis
- Basic molecular biology
- Work with Principal Investigator to establish and maintain best lab practices and techniques (e.g. experimental methods, lab policies and procedures, safety guidelines, equipment operation)
- Maintain excellent records (primarily electronic) of best lab practices and techniques
- Assist Principal Investigator in the general training of new laboratory personnel
- Closely collaborate with other team members in the support and management of various projects
- Assist in the setup of laboratory equipment
- Oversee maintenance of laboratory equipment and general laboratory organization
- Procure, organize, and regularly inventory/purchase equipment and supplies
- Ensure Laboratory Biosafety Protocol and personnel safety training is kept up to date
- Clearly communicate data and results to project stakeholders
- Carry out scientific literature reviews when necessary
- Assist Principal Investigator or other lab members in the preparation of manuscripts and grants
To perform this job successfully, the candidate must be able to perform each primary duty satisfactorily. The ideal candidate will strive to perform each task exceptionally.
The requirements listed below are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the primary duties.
Education and Experience
- The candidate will hold a B.S. or higher in biochemistry, (molecular) biology, biological engineering, or a related discipline.
- The candidate will have at least 3 years of training in relevant laboratory research, and strong preference will be given to those applicants that have direct experience working with specific experimental methods highlighted above, especially in molecular biology and/or mammalian cell culture
- The ideal candidate will also have experience in non-experimental responsibilities outlined above, and a track record of listed authorship in peer-reviewed journals
Knowledge, Skills and Abilities Required
- Strong background knowledge of molecular biology, biochemistry, and data analysis
- Strong knowledge and experience with relevant scientific procedures and experimental techniques
- Strong initiative and dedication to scientific research
- Strong organizational skills and attention to detail
- Strong interpersonal and communication (oral and written) skills
- Working knowledge of experimental design and understanding of laboratory equipment
- Ability to work independently and collaboratively
- Ability to train others
Qualified individuals interested in this opportunity are required to submit a cover letter and curriculum vitae, and contact information of three references, as one document via the online career portal.