Cardiac morphogenesis and function in zebrafish: the cardiac jelly
Over the past years, the Huisken lab has developed unique microscope systems to image and visualize zebrafish heart morphogenesis and function in vivo. Using a selective plane illumination microscope (SPIM) to capture the beating heart in 6D (x, y, z, t: time-point in cardiac cycle, T: time in development, color), I want to understand the mechanical properties of the developing zebrafish heart and how it functions as a pump. Of primary interest is the role of the embryonic cardiac jelly (CJ), a gel-like extracellular matrix (ECM) between the endocardium and myocardium.
Bachelor and Master in Biology at the University of Geneva, Switzerland (2011-2016)
PhD student in the Huisken lab at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany. Part of the Dresden International PhD Program (DIPP).
Guest student at the Morgridge Institute for Research (since 2016)