Janice Pennington

Janice Pennington

Research Specialist

Area:

Phone:

(317) 420-3676

Email:

[javascript protected email address]

I use various techniques in electron microscopy, including cryo-electron tomography, to study the structure of the RNA replication machinery of positive-strand RNA viruses.

Education

M.S. Botany, 1985, Oklahoma State University

B.S. Biology, 1979, Oklahoma State University

Selected Publications

  • Buono RA, Leier A, Paez-Valencia J, Pennington J, Goodman K, Miller N, Ahlquist P, Marquez-Lago TT, Otegui MS. ESCRT-mediated vesicle concatenation in plant endosomes. J Cell Biol. 2017 Jul 3;216(7):2167-2177. doi: 10.1083/jcb.201612040. Epub 2017 Jun 7. PMID: 28592443
  • Unchwaniwala N, Zhan H, Pennington J, Horswill M, den Boon JA, Ahlquist P. Subdomain cryo-EM structure of nodaviral replication protein A crown complex provides mechanistic insights into RNA genome replication. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18680-18691. doi: 10.1073/pnas.2006165117. Epub 2020 Jul 20. PMID: 32690711
  • Sibert BS, Navine AK, Pennington J, Wang X, Ahlquist P. Cowpea chlorotic mottle bromovirus replication proteins support template-selective RNA replication in Saccharomyces cerevisiae. PLoS One. 2018 Dec 26;13(12):e0208743. doi: 10.1371/journal.pone.0208743. eCollection 2018. PMID: 30586378
  • Ertel KJ, Benefield D, CastaƱo-Diez D, Pennington JG, Horswill M, den Boon JA, Otegui MS, Ahlquist P. Cryo-electron tomography reveals novel features of a viral RNA replication compartment. Elife. 2017 Jun 27;6:e25940. doi: 10.7554/eLife.25940. PMID: 28653620