Updates from the Lab

  • 2018

    August

    Dr. Rachel Guerra joins the lab as a Postdoctoral Fellow after completing her thesis work with Professor Loren Walensky at Harvard University.

    Andrew Sung (MSTP) joins the lab.

    Laura Steenberge (MSTP) joins the lab.

    June

    CMB student Jonathan Schmitz passes his preliminary examination to advance to candidacy.

    Dr. Zakery Baker joins the lab as a Morgridge Postdoctoral Fellow after completing his thesis work with Professor Scot Leary at the University of Saskatchewan in Canada.

    May

    Lainy Von Bank receives her degree in Molecular Biology from the University of Wisconsin-Madison. Lainy will remain in the lab.

    IPiB student Nathan Murray passes his preliminary examination to advance to candidacy.

    IPiB student Edrees Rashan passes his preliminary examination to advance to candidacy.

    April

    Zachary Kemmerer is chosen to receive a William H. Peterson Fellowship through the Department of Biochemistry.

    Danielle Lohman is selected as a AAAS Science and Technology Policy fellow finalist.

    Nate Murray receives an NSF Graduate Research Fellowship.

    January

    Naomi Ptak joins the lab.

  • 2017

    December

    Our multi-omics analysis of the mitochondria-related mRNA binding protein, Puf3p, co-led by Chris Lapointe (of the Wickens group) and Jon Stefely, was published in Cell Systems.

    Our mitoprotease profiling paper that revealed a role for Oct1p in CoQ biosynthesis, led by Mike Veling, was published in Molecular Cell.

    Our manuscript describing lipid and small molecule modulators of COQ8, led by Andrew Reidenbach, was published in Cell Chemical Biology.

    Abigail Bartlett (IPiB) joins the lab as first year graduate student.

    November

    Jonathan Tai (MSTP) joins the lab.

    Jaclyn Mabry joins the lab as a Research Specialist.

    October

    IPiB student Danielle Lohman successfully defends her thesis entitled, “Protein-and lipid-binding features of COQ9 and its role in coenzyme Q biosynthesis”. Danielle will remain in the lab as a postdoctoral fellow.

    Andrew Reidenbach leaves the lab to join the Broad Institute as a Research Scientist.

    September

    Our review article on the biochemistry of coenzyme Q biosynthesis, led by Jon, is published in Trends in Biochemical Sciences.

    Adam Jochem receives the 2017 Pagliarini Lab Award. This award recognizes Adam for his consistent and selfless efforts to improve our science and enhance our lab culture.

    Undergraduate Sheila Johnson joins the lab.

    Michael Veling is one of six recipients of the 2017 IPiB Research Poster Award.

    August

    Rahul Gupta leaves the lab to start medical school in the Harvard-MIT HST Medical Sciences Program at Harvard Medical School.

    Jacob Sokol leaves the lab to teach English as a second language in Spain.

    July

    Natalie Niemi is awarded a spot in the Molecular and Applied Nutrition Training Program (MANTP) in the Department of Nutritional Sciences at the University of Wisconsin.

    June

    Jon Stefely (MSTP) returns to medical school (M3) and starts his clinical rotations.

    Amy Lin joins the lab as a Graphic Design Student Assistant.

    May

    Our work defining Ptc6p as the yeast pyruvate dehydrogenase phosphatase, led by Xiao, is published in Journal of Biological Chemistry.

    Nathan Murray is awarded a spot on the Chemistry-Biology Interface Training Program (CBI) T32.

    IPiB student Kyle Robinson passes his preliminary examination to advance to candidacy.

    Rahul Gupta is accepted into the Harvard-MIT HST Medical Sciences Program at Harvard Medical School. He will pursue an MD, dually enrolled at Harvard Medical School and MIT.

    Jacob Sokol receives his degree in Biology from the University of Wisonsin-Madison. Jacob will remain in the lab for the summer.

    Mike Drahnak leaves the lab to continue his education and pursue a medical degree.

    April

    Dave receives the 2017 Protein Science Young Investigator Award.

    IPiB student Andrew Reidenbach successfully defends his thesis entitled, "Activities and activators of the atypical kinase COQ8 and its role in coenzyme Q biosynthesis”.

    Keith Kamer receives a 2017 Sophomore Research Fellowship.

    Michael Veling is chosen to receive the William R. & Dorothy E. Sullivan Wisconsin Distinguished Graduate Fellowship award through the Department of Biochemistry.

    March

    Kyle Robinson receives an NSF Graduate Research Fellowship.

    Brendan Floyd is matched with the Lucille Packard Children's Hospital, Pediatrics Program/Research Track at Stanford University.

    February

    Chemistry student Xiao Guo successfully defended her thesis entitled, "Defining the molecular function of mitochondrial phosphatases".

    January

    Keith Kamer joins the lab.

    Our work describing the function of the poorly characterized mitochnondrial matrix phosphatase Ptc7p, led by Xiao and Natalie, is published in Cell Reports.

  • 2016

    December

    Nathan Murray (IPiB), Edrees Rashan (IPiB), and Jonathan Schmitz (CMB) join the lab as first year graduate students.

    Mike Drahnak receives his degree in Biochemistry from the University of Wisconsin - Madison. Mike will remain in the lab as a temporary research assistant.

    November

    Rahul Gupta joins the lab as a Temporary Research Assistant after completing his undergraduate work at the University of Pennsylvania.

    October

    The Pagliarini Lab is profiled in the Fall 2016 issue of GROW Magazine, Wisconsin's magazine for the life sciences.

    September

    Our collaborative "Y3K" work with the Coon Group describing a multi-omic strategy to characterize the functions of mitochondrial proteins, led by Jon Stefely and Nick Kwiecien, is published in Nature Biotechnology.

    Dr. Mateusz Manicki joins the lab as a Morgridge Postdoctoral Fellow after completing his thesis work with Professor Jaroslaw Marszalek at the University of Gdansk in Poland.

    August

    Kyle Robinson is awarded a spot on the Biology of Aging and Age-Related Disease T32.

    Our collaborative work with the Denu group describing the epigenetic regulation of mitochondrial biogenesis in response to iron deprivation is published in JBC.

    Our collaborative work with the Puccio group and others describing the unorthodox function of COQ8A in coenzyme Q biosynthesis, led by Jon Stefely and Floriana Licitra, is published as an Article in Molecular Cell.

    Our collaborative work with the Coon group and others to map the protein-protein interactions and functions of uncharacterized mitochondrial proteins (MXPs) work mapping is published as an Article in Molecular Cell.

    Stories about Pagliarini Lab work are featured in multiple media outlets, including EurekaAlert, Mitochondrial Disease News, and GenomeWeb.

    July

    A collaborative NIH P41 grant to establish the National Center for Quantitative Biology of Complex Systems is award to Josh Coon (PI), Dave Pagliarini (Co-I) and Lingjun Li (Co-I), and is featured on GenomeWeb

    April

    Mike Drahnak receives a 2016 Hilldale Undergraduate/Faculty Research Fellowship.

    The Pagliarini, Coon, and Craven labs were awarded one of the 14 inaugural UW2020 grants.

    Dave is awarded the 2016 CALS Pound Award for outstanding early career research.

    March

    Matt Stefely is accepted into UC-Berkeley's MCB Program.

    Mateusz Manicki, currently a graduate student in Dr. Jaroslaw Marszalekâ's lab at the University of Gdansk in Gdansk, Poland will join us this fall as a Morgridge Postdoctoral Fellow.

    Dave's R01 proposal entitled, "Systematic functional annotation of the mitochondrial proteome" is funded by NIGMS.

    February

    Dave receives the Presidential Early Career Award for Scientists and Engineers (PECASE).

  • 2015

    December

    Kyle Robinson (IPiB) joins the lab as first year graduate student.

    September

    CMB student Jarred Rensvold successfully defended his doctoral thesis entitled, "Adaptive mitochondrial biogenesis response to iron deprivation." Jarred will remain with the lab as an Assistant Scientist.

    August

    Dave is selected to direct the Morgridge Metabolism Theme. The lab moves into the Morgridge Institute for Research on campus.

    Undergraduate Isabel Johnson enrolls as PhD student in UCSF's Tetrad Program.

    July

    IPiB student Jonathan Stefely successfully defended his doctoral thesis entitled, "Biochemical functions of mitochondrial ADCK3 and other coenzyme Q biosynthesis proteins." Jon will remain with the lab as a postdoctoral fellow.

    June

    Dave is promoted to Associate Professor with tenure

    Andrew accepted an internship at Amgen in Thousand Oaks, CA from June through August.

    May

    IPiB student Brendan Floyd successfully defended his thesis entitled, "Characterization of orphan mitochondrial proteins via quantitative interaction mapping."

    Brendan Floyd receives a 2015 Denton Award for Graduate Student Excellence in Teaching and Mentoring.

    Matt Stefely receives a 2015 Hilldale Undergraduate/Faculty Research Fellowship.

    IPiB student Mike Veling passes his preliminary examination to advance to candidacy

    Isabel Johnson is accepted into the UCSF Tetrad Program.

    IPiB student Molly McDevitt receives a biochemistry departmental fellowship.

    March

    Andrew Reidenbach receives a Louis and Elsa Thomsen Distinguished Graduate Fellowship.

    Mike Veling receives an NSF graduate research fellowship.

    CMB student Josh Carson successfully defended his thesis entitled, "Regulation of mitochondria by reversible protein phosphorylation."

    IPiB student Amelia Nestler successfully defended her thesis entitled, "Impact of dynamic post-translational modifications on the activities of mitochondrial proteins."

  • 2014

    December

    Dave is a named as a recipient of a 2015-2016 UW-Madison Vilas Associate Award.

    Our recent work on the biosynthesis of coenzyme Q is featured in the UW-Madison news and various other medias outlets.

    Zack Kemmerer (IPiB) and Holly Cho (CMB) join the lab as first year graduate students.

    Our work describing the structure and function of the mitochondrial kinase ADCK3, led by Jon Stefely and Andrew Reidenbach, is published as an Article in Molecular Cell.

    October

    Danielle Lohman's paper describing the structure and function of COQ9 is published as a direct submission in PNAS.

    A joint project with the Senes Lab describing the transmembrane domain of ADCK3 is published in JACS.

    Brendan Floyd is one of three recipients of the 2014 IPiB Retreat Best Poster Award.

    Michael Drahnak, a sophomore biochemistry major and Biochemistry Scholar, joins the lab.

    July

    Dave's R01 proposal entitled, "Establishing the role of the atypical kinase ADCK3 in mitochondrial metabolism" is funded by NIGMS.

    June

    Paul Grimsrud accepts a Research Scientist position at the Duke Molecular Physiology Institute.

    Local high school student Alexa Jaume, who spent two summers in our lab as part of the NIH STEP-UP program, will enroll at UPenn this fall.

    May

    Chemistry graduate student Xiao Guo passes her original research proposal exam to advance to candidacy.

    April

    IPiB student Danielle Lohman passes her preliminary exam to advance to candidacy.

    Brendan Floyd receives a Louis and Elsa Thomsen Distinguished Graduate Fellowship.

    Danielle Lohman receives an NSF graduate research fellowship.

    Isabel Johnson is honored with a Hilldale Undergraduate/Faculty Research Fellowship.

  • 2013

    December

    A review article co-authored by Dave and Jared Rutter (Utah), entitled "Hallmarks of a new era in mitochondrial biochemistry," is published in Genes and Development.

    Michael Veling (IPiB) joins the lab.

    September

    CMB student Kelly Werner passes her preliminary exam to advance to candidacy.

    August

    Amal Javaid and Matthew Stefely join the lab.

    Andrew Reidenbach is a awarded a spot on the Chemistry-Biology Interface Training Program.

    July

    Jarred Rensvold receives a Louis and Elsa Thomsen Distinguished Graduate Fellowship.

    Our manuscript describing the dynamic nature of mitochondrial acetylation and its role in regulating the metabolic enzyme Acat1, led by Amelia Still, Brendan Floyd, and Alex Hebert, is published in the Journal of Biological Chemistry.

    May

    Chemistry graduate student Xiao Guo passes her Thesis Background Oral (TBO).

    Natalie Niemi receives a postdoctoral fellowship from the United Mitochondrial Disease Foundation.

    April

    IPiB graduate students Andrew Reidenbach, Jon Stefely, and Molly McDevitt pass their preliminary exams to advance to candidacy.

    Brendan Dolan's Senior Thesis grant proposal is selected for funding by the Faculty Honors Committee.

    Drew Gunderson is honored with a Hilldale Undergraduate/Faculty Research Fellowship.

    March

    Dave's R01 proposal entitled "Regulation of Mitochondrial Metabolism by Post-Translational Modifications" is funded by NIDDK.

    Drew Gunderson receives a summer fellowship to study abroad at the RIKEN Institute in Japan.

    January

    Temi Ayodele (junior), Sarah Bohl (freshman) and Nicole Wittkopp (freshman) join the lab.

    Drew Gunderson is selected to present at the 2013 National Conference on Undergraduate Research.

    Our manuscript describing the role of iron in regulating mitochondrial biogenesis, led by Jarred Rensvold, is published in Cell Reports.

  • 2012

    December

    Danielle Lohman (IPiB) joins the lab.

    November

    Our manuscript describing the dynamic nature of mitochondrial protein phosphorylation, led by Paul Grimsrud and Josh Carson, is published in Cell Metabolism.

    October

    Danielle Lohman (IPiB) begins her rotation.

    August

    We say goodbye to Grant Barber as he leaves the lab to continue his education as a medical student at Harvard Medical School.

    Chelsea Krause heads off to Boston University to continue her academic endeavors as graduate student.

    Natalie Niemi (postdoctoral fellow) joins the lab.

    July

    AJ Bureta receives 1st place in the 2012 Proteomics Photo & Graphic Art Contest.

    Ethan Martin (senior biology major) joins the lab.

    Jon Stefely receives a predoctoral fellowship (NIH F30) from the National Institutes of Health.

    May

    Dave is named a 2012 Shaw Scientist. The Shaw Award - a $200,000 unrestricted prize - provides needed support to young scholar-scientists engaged in groundbreaking research in the fields of genetics, cell biology and cancer research at critical stages in their careers.

    Brendan Floyd (IPiB) joins the lab.

    April

    Athavi Jeevananthan is honored with a Hilldale Undergraduate/Faculty Research Fellowship.

    Andrew Reidenbach and Molly McDevitt receive Honorable Mention for their NSF Graduate Fellowship Applications.

    Chelsea Krause is accepted into the Forensic Sciences Graduate Program at Boston University.

    March

    Athavi Jeevananthan is accepted into the Khorana Program, a highly competitive summer research program that swaps talented undergraduates from the US and India for approximately 10 weeks.

    Grant Barber is accepted to Harvard Medical School.

  • 2011

    December

    Xiao Guo (Chemistry), Molly McDevitt (IPiB), Andrew Reidenbach (IPiB) and Kelly Werner (CMB) join the lab.

    Natalie Niemi, currently a graduate student in Dr. Jeffrey MacKeigan's lab at the Van Andel Institute in Grand Rapids, Michigan, will join us as a postdoctoral fellow next summer.

    Josh Carson is awarded a two year graduate fellowship from the American Heart Association.

    November

    Michael Bellecourt (IPiB) and Xiao Guo (Chemistry) begin their rotations.

    October

    Josh Neuman (Nutritional Sciences) begins his rotation.

    Kelly Werner (CMB), Molly Mcdevitt (IPiB) and Andrew Reidenbach (IPiB) begin their rotations.

    September

    Samantha Durbin (sophomore biology major) and Zach Meyer (sophomore biochemistry major) join the lab.

    Ellen Crummy (IPiB), Laura Bond (IPiB) and Yefim Zaltsman (IPiB) begin their rotations.

    Paul Grimsrud receives a postdoctoral fellowship (NRSA F32) from the National Institutes of Health for studying liver mitochondrial dysfunction in type 2 diabetes.

    August

    The Pagliarini Lab is featured in the UW News.

    July

    Chelsea Krause (senior biology major) joins the lab.

    Jarred Rensvold passes his preliminary exam to advance to candidacy.

    We say goodbye to Anna Engstrom as she continues her academic endeavors as a graduate student of the University of Washington.

    Dave receives a 2011 Glenn Foundation for Medical Research Award.

    Jon Stefely passes the first step of his US Medical Licensing Examination.

    Josh Carson passes his preliminary exam to advance to candidacy.

    May

    Amelia Still passes her preliminary exam to advance to candidacy.

    April

    Dave is named a 2011 Searle Scholar.

    Junior Biochemistry major, Grant Barber, is honored with a Hilldale Undergraduate/Faculty Research Fellowship.

    March

    Sophmore Biochemistry/Statistics major, Wei Jiang, is awarded a Welton Summer Sophomore Honors Apprenticeship.

    February

    Junior Biochemistry major, Grant Barber, is one of six undergraduates selected to participate in the Summer Cambridge and Oxford Research Experience (SCORE) program.

  • 2010

    December

    Mark Sarcone (IPiB) joins the lab.

    Paul Grimsrud (Post-Doctoral Fellow) and AJ Bureta (Graphic Designer) join the lab.

    November

    Adam Jochem joins the lab as a Senior Research Specialist.

    October

    Sarah Wessel (IPiB), Funita Phan (IPiB) and Tyler Duellman (MCP) begin their rotations.

    September

    Kelly Stecker (IPiB) and Mark Sarcone (IPiB) begin their rotations.

    August

    Jon Stefely (MSTP) joins the lab (will begin research in 2011).

    Athavi Jeevanathan (sophomore biochemistry major) joins the lab as a Biochemistry Scholar.

    July

    Dave and John Markley are awarded an NIH U01 award to create the "Mitochondrial Protein Partnership" at UW-Madison.

    Pagliarini Lab featured in the 2010 CMB alumni newsletter (article by Jarred Rensvold and Josh Carson).

    May

    Anna Engstrom (senior pharmacology/toxicology major) and Wei Jiang (sophomore biochemistry/statistics major) join the lab.

    Jon Stefely (MSTP) begins his rotation.

    April

    Amelia Still is awarded an NSF Graduate Research Fellowship.

  • 2009

    December

    Amelia Still (IPiB), Josh Carson (CMB) and Jarred Rensvold (CMB) join the lab.

    November

    Jarred Rensvold (CMB), Lee Behling (IPiB) and Amelia Still (IPiB) begin their rotations.

    October

    Doug Porter (IPiB), Ryan Petty (IPiB) and Eui-Seok Shin (CMB) begin their rotations.

    September

    Chris LaPointe (IPiB) and Josh Carson (CMB) begin their rotations.

    August

    Dave is awarded an NIH RC1 "Challenge Grant" to study mitochondrial dysfunction in Type II Diabetes.

    Nick Ryan joins the lab as an Assistant Research Specialist.

    Grant Barber (sophomore biochemistry) and Kate Stone (freshman biology) join the lab.

    July

    Dave joins the UW-Madison Biochemistry faculty.