Positive-strand RNA viruses constitute many clinically relevant pathogens, including Hepatitis C, SARS, zika-, Dengue, and poliovirus. A common feature of this group of viruses is that, upon infection, the first proteins expressed restructure the host intracellular membranes to from viral replication compartments. I am specifically interested in studying the structural features of these multifunctional proteins. […]
The work in the Wright lab uses cryo-EM to investigate the structures of many types of cells. We also develop methods for advancing this technology. The goal is to use this information to aid in the development of novel antimicrobials, therapeutics, and vaccines.
In my research, I apply machine learning algorithms to problems in biology. Recent technology has enabled geneticists to perform high-throughput experiments in which all genes are measured in response to a stimulus. I look for patterns in these data which are consistent with prior research on biological pathways: the interactions among groups of genes which […]
I am interested in developing new algorithms in analyzing biological time series data. My research uses statistical methods to identify gene-gene interactions and differentially expressed genes. Education BS, 2014, University of Wisconsin-Madison
I am a graduate researcher working with Tony Gitter in the virology group. My research interests include computational methods for analyzing tumor heterogeneity, driver gene identification in cancer, and detecting bias in biological network analyses.