High-throughput computing, HIV and the mystery of ‘elite controllers’

In August 2015, just before going on vacation, virology researcher Dave O’Connor teed up the largest data analysis challenge of his lifetime. The computing run included 694 independent jobs, each one with about one billion points of genomic data to process. O’Connor returned to find that his “set it and forget it” gamble paid off handsomely: 693 of the 694 computing runs had fully completed, with zero human intervention.