Our group uses zebrafish as the primary model organism to investigate the mechanisms of innate tissue regeneration. We view tissue regeneration as a coordinated, whole-organism event, involving both local repair processes and remote injury responses. At the local level, our focus is on the highly regenerative zebrafish heart, where we explore novel cellular and molecular mechanisms underlying epicardial cell-mediated cardiac regeneration. At the remote level, we aim to uncover the collective role of multiple organ systems in orchestrating tissue regeneration. To this end, we develop novel genetic tools and research platforms to identify uninjured organs responding to injury and long-range signals that guide the regeneration of damaged tissues from these remote organs.
Education
B.S., 2014, Hong Kong University of Science and Technology
Ph.D., 2022, Duke University