Morgridge Institute for Research Fearless Science

The Challenges that Motivate Us

Morgridge Institute scientists recognize that a fundamental understanding of human biology will drive the next big advances in human health. We conduct "fearless science" in some of these promising frontiers.

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Finding a weak link in the frightful parasite Schistosoma

The parasitic disease schistosomiasis is one of the developing world's worst public health scourges, affecting hundreds of millions of people, yet only a single, limited treatment exists to combat the disease. Researchers are searching for potential new targets by probing the cellular and developmental biology of the parasitic flatworm Schistosoma.Read more >

Lipid species offer insights into metabolic health

Two new Morgridge Institute for Research studies suggest the current tests, which measure the abundance of lipid classes, are insufficient. Rather, lipids identified and studied at the individual species level—instead of grouped in classes—may be better signatures of metabolic health.Read more >

Immortal: An oral history of stem cell discovery

In November 1998, the journal Science published James Thomson’s groundbreaking work on embryonic stem cells. There has been 20 years of progress since the initial discovery spawned a new field of research, and tremendous potential exists for the future. We reached out to the people who lived it, and they shared the experiences in their own words. This is their story. Read more >

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