The Bartels lab develops new imaging technologies to expand the frontiers of biomedical research. Our goal is to develop new tools to observe phenomena that are difficult or even impossible to capture with current imaging tools and biological assays. Our focus is on optical imaging because of its unique ability to resolve spatial scales ranging from sub-cellular structures such as organelles to large regions of tissue in order to understand morphological changes associated with disease. Crucially, optical imaging also allows us to observe the dynamics of biological processes in real time, as it can be safely implemented in live biological specimens. We team up with diverse biomedical scientists to collaborate and apply these unique tools to answer questions that are critical to growing our understanding of biological sciences. These questions range from fundamental biological unknowns to best approaches for developing translational tools to be used in the clinic. Thus, our projects cover diverse fields spanning from optical and quantum physics, advanced computation and algorithms, to fundamental and clinical biology.