Author: Brian Mattmiller

Stem cells help predict neural toxicity

A new system developed by scientists at the Morgridge Institute for Research and the University of Wisconsin–Madison may provide a faster, cheaper and more biologically relevant way to screen drugs and chemicals that could harm the developing brain.

Q&A with New Morgridge Metabolism Director Dave Pagliarini

Dave Pagliarini, UW–Madison associate professor of biochemistry, has been selected to lead the Morgridge Institute Metabolism Initiative, which will provide leadership, infrastructure and community building to this growing UW–Madison research area. Pagliarini, an expert on mitochondria structure and function, reflects on some of the opportunities ahead.

Algorithm helps identify elusive genes that express like clockwork

The genes that turn on and off in precisely timed patterns, known as oscillatory genes, play an essential role in development functions like cell division, circadian rhythms and limb formation. But without a time-lapse view of genetic expression, these genes have gone largely undiscovered.