Researchers from the Morgridge Institute for Research and the Murdoch Children’s Research Institute (MCRI) in Australia have devised a way to dramatically cut the time involved in reprogramming and genetically correcting stem cells, an important step to making future therapies possible.
Author: Brian Mattmiller
High-throughput computing, HIV and the mystery of ‘elite controllers’
In August 2015, just before going on vacation, virology researcher Dave O’Connor teed up the largest data analysis challenge of his lifetime. The computing run included 694 independent jobs, each one with about one billion points of genomic data to process. O’Connor returned to find that his “set it and forget it” gamble paid off handsomely: 693 of the 694 computing runs had fully completed, with zero human intervention.
Stem cells help predict neural toxicity
A new system developed by scientists at the Morgridge Institute for Research and the University of Wisconsin–Madison may provide a faster, cheaper and more biologically relevant way to screen drugs and chemicals that could harm the developing brain.
Ossorio to help steer National Academies Initiative on human gene editing
Pilar Ossorio, the Morgridge Institute for Research bioethicist in residence, will serve on an international committee convened by the National Academies of Science (NAS) to address the ethically challenging frontiers of human gene editing technology.
Q&A with New Morgridge Metabolism Director Dave Pagliarini
Dave Pagliarini, UW–Madison associate professor of biochemistry, has been selected to lead the Morgridge Institute Metabolism Initiative, which will provide leadership, infrastructure and community building to this growing UW–Madison research area. Pagliarini, an expert on mitochondria structure and function, reflects on some of the opportunities ahead.
