In order to understand the biochemical underpinnings of disease, it is imperative to shrink down to the molecular level. It’s this mentality that steered Mateusz Manicki all the way from Poland’s Gdansk University to Madison, Wisconsin to study mitochondrial proteins. Manicki will be using mass spectrometry resources to better understand the functionality of cells contributing to a given disease.
The Laboratory of Biomolecular Mass Spectrometry (LBMS), launched in summer 2015, accelerates the university’s ability to apply this powerful technology to high-impact projects, says Joshua Coon, UW-Madison professor of chemistry and biomolecular chemistry and LBMS director.
Mitochondria are the engines that drive cellular life, but these complex machines are vulnerable to a wide range of breakdowns, and hundreds of their component parts remain a functional mystery.
Can we fight cancer by targeting its metabolism, essentially starving tumors of the nutrients they need to survive? It’s one of the intriguing big-picture questions in the research field of Jing Fan, a new investigator in the Morgridge Institute for Research metabolism theme.
It’s not every day someone gets the chance to stroll through the East Wing of the White House, snapping photos and checking out its famous Blue Room and Red Room. Dave Pagliarini experienced that and more during his trip to the nation’s capital May 5-6 to receive his Presidential Early Career (PECASE) award.