Category: Metabolism

Cracking the code of coenzyme Q biosynthesis

Coenzyme Q (CoQ) is a vital cog in the body’s energy-producing machinery, a kind of chemical gateway in the conversion of food into cellular fuel. But six decades removed from its discovery, scientists still can’t describe exactly how and when it is made.

Mateusz Manicki: Collaboration breeds scientific opportunity

In order to understand the biochemical underpinnings of disease, it is imperative to shrink down to the molecular level. It’s this mentality that steered Mateusz Manicki all the way from Poland’s Gdansk University to Madison, Wisconsin to study mitochondrial proteins. Manicki will be using mass spectrometry resources to better understand the functionality of cells contributing to a given disease.

Tech investment spurs Alzheimer’s research

The Laboratory of Biomolecular Mass Spectrometry (LBMS), launched in summer 2015, accelerates the university’s ability to apply this powerful technology to high-impact projects, says Joshua Coon, UW–Madison professor of chemistry and biomolecular chemistry and LBMS director.