In new findings in Nature, a team at the Morgridge Institute for Research and Washington University School of Medicine in St. Louis analyzed dozens of ‘orphan’ mitochondrial proteins and suggested functions for many of them — an important step to finding better ways to diagnose and treat poorly understood human conditions.
In new research in Nature Communications, the Joshua Coon Lab describes a game-changing advance that unites the power of mass spectrometry with the potential of electron microscopy (EM) — a finding that could transform biotechnology.
Using tiny specks of dental plaque, scientists at the Morgridge Institute for the first time compiled a sophisticated analysis that opens the door to using the trove of micro-organisms in your mouth as an indicator of other health issues.
Morgridge investigator Josh Coon’s unique project marrying mass spectrometry technology to the everyday toilet is tabbed as one of the trends to watch in the Wall Street Journal’s “Future of Everything” series.
Researchers have identified more than 200 molecular features that strongly correlate with COVID-19 severity.
Why is it that some COVID-19 patients become extremely ill and die, while others experience only mild symptoms? A new study uses mass spectrometry, RNA sequencing, and machine learning to explore the molecular traits that might influence the severity of the disease.
Morgridge investigator Josh Coon describes how “smart toilets” could be the new frontier in personalized medicine.
An Albany Med physician who has been caring for COVID-19 patients during the pandemic is partnering with the Morgridge Institute and UW-Madison to study why some patients experience COVID-19 more severely than others.
In the center of the COVID-19 pandemic, many hospitals are racing to maintain quality care for patients with severe disease while facing a shortage of resources and limited understanding of the novel coronavirus.
via USA Today
Scientists at the University of Wisconsin think their “smart toilet” is capable of monitoring your health and discovering early signs of diseases.
Wearable, smart technologies are transforming the ability to monitor and improve health, but a decidedly low-tech commodity — the humble toilet — may have potential to outperform them all.
Katherine Overmyer, a former Morgridge postdoctoral fellow, was named the associate director of the Laboratory for Biomolecular Mass Spectrometry (LBMS) at UW-Madison.
A new chair at the Morgridge Institute for Research takes aim at osteoarthritis, a debilitating and painful disease that affects more than 27 million Americans. Currently, osteoarthritis is largely treated with palliative care to help patients alleviate their symptoms.
Proteins are the workhorse molecules that perform all the functions in the cell and the body. Being able to detect and measure proteins is critical to figuring out basic biology, and the signature of diseases such as Alzheimer’s, cancer and diabetes. Josh Coon is creating technologies to do exactly that.
The Laboratory of Biomolecular Mass Spectrometry (LBMS), launched in summer 2015, accelerates the university’s ability to apply this powerful technology to high-impact projects, says Joshua Coon, UW-Madison professor of chemistry and biomolecular chemistry and LBMS director.
The Morgridge Institute for Research, as part of its Metabolism Initiative, is working with a University of Wisconsin-Madison team to greatly expand the scope of “mass spec” applications on campus. A new resource housed in the UW-Madison Biotechnology Center brings together a multi-million dollar investment in mass spectrometry tools from multiple sources to form a central repository to tackle large-scale investigations.
In a study published today (Sept. 11), researchers at the University of Wisconsin-Madison report the first full measurement of the proteins made by both types of stem cells. In a study that looked at four embryonic stem cells and four IPS cells, the proteins turned out to be 99 percent similar, says Joshua Coon, an associate professor of chemistry and biomolecular chemistry who directed the project.