Selected Publications

  • Bruce JW, Bracken M, Evans E, Sherer N, Ahlquist P. (2021) ZBTB2 represses HIV-1 transcription and is regulated by HIV-1 Vpr and cellular DNA damage responses. PLoS Pathogens 17:e1009364.
  • Unchwaniwala N, Zhan H, den Boon JA, Ahlquist P. (2021) Cryo-electron microscopy of nodavirus RNA replication organelles illuminates positive-strand RNA virus genome replication. Current Opinion in Virology 51:74-79.
  • Benner BE, Bruce JW, Kentala JR, Murray M, Becker JT, Garcia-Miranda P, Ahlquist P, Butcher SE, Sherer NM. (2021) Perturbing HIV-1 ribosomal frameshifting frequency reveals a cis preference for Gag-Pol incorporation into assembling virions.  Journal of Virology  JVI01349-21 (in press).
  • Nishikiori, M and Ahlquist P.  (2021)  Transmembrane redox regulation of genome replication functions in positive-strand RNA viruses.  Current Opinion in Virology 47:25-31.
  • Unchwaniwala N and Ahlquist P.  (2020) Coronavirus dons a new crown.  Science 369:1306-1307.
  • Unchwaniwala N, Zhan H, Pennington J, Horswill M, den Boon JA and Ahlquist P. (2020) Subdomain cryo-EM structure of nodaviral replication protein A crown complex provides mechanistic insights into RNA genome replication. Proc Natl Acad Sci U S A. 117:18680-18691.
  • Nishikiori M and Ahlquist P. (2018) Organelle Luminal Dependence of (+)strand RNA Virus Replication Reveals a Hidden Druggable Target.  Science Advances  4:eaap8258.
  • Ertel KJ, Benefield D, Castaño-Diez D, Pennington J, Horswill M, den Boon JA, Otegui MS, Ahlquist P.  (2017)  Cryo-Electron Tomography Reveals Novel Features of a Viral RNA Replication Compartment.  eLife 6:e25940.
  • Spurgeon M, den Boon J, Horswill M, Barthakur S, Forouzan O, Rader J, Beebe J, Roopra A, Ahlquist P, and Lambert PF. (2017) Human Papillomavirus Oncogenes Reprogram the Cervical Cancer Micro-environment Independently of and Synergistically with Estrogen. Proc Natl Acad Sci USA 114:E9076-E9085.
  • Pocock GM, Becker JT, Swanson CM, Ahlquist P, Sherer NM. (2016) HIV-1 and M-PMV RNA Nuclear Export Elements Program Viral Genomes for Distinct Cytoplasmic Trafficking Behaviors.  PLoS Pathogens 12:e1005565.
  • den Boon J,  Pyeon D, Wang S, Horswill M, Schiffman M, Sherman M, Zuna R, Wang Z, Hewitt S, Pearson R, Schott M, Chung L, He Q, Lambert P, Walker J, Newton M, Wentzensen N, and Ahlquist P (2015)  Molecular Transitions from Papillomavirus Infection to Cervical Precancer and Cancer: Role of Stromal Estrogen Receptor Signaling.  Proc Natl Acad Sci USA 112:E3255-64.
  • Diaz A, Zhang J, Ollwerther A, Wang X, and Ahlquist P.  (2015)  Host ESCRT Proteins Are Required for Bromovirus RNA Replication Compartment Assembly and Function.  PLoS Pathogens 11:e1004742 (26 pages).
  • Chasman, D., B. Gancarz, L, Hao, M. Ferris, P, Ahlquist and M. Craven.  (2014)  Inferring host gene subnetworks involved in viral replication. PLoS Comput Biol 10:e1003626 (22 pp).
  • Bruce, J., R. Reddington, E. Mathieu, M. Bracken, J.A. Young and P. Ahlquist (2013)  ZASC1 stimulates HIV-1 transcription elongation by recruiting P-TEFb and TAT to the LTR promoter. PLoS Pathogens 10: e1003712.