Tag: coon lab

Rising Sparks: Katherine Overmyer, Metabolism

Katie Overmyer collaborates with metabolism researchers to push the boundaries of mass spectrometry technology and uncover answers to important biological questions.

Pounding out the dents: Westphall’s career solved problems, advanced discovery

Mike Westphall, a distinguished scientist in the Josh Coon Lab, will retire this month after a legacy of developing cool tools in the name of scientific discovery.

Researchers illuminate HIV in cell-to-cell attack mode

When cells infected with HIV make contact with uninfected cells, a new study reveals how that connection unleashes a hornet’s nest of activity that helps drive transmission.

‘Deep proteome’ project provides atlas for human complexity

The Josh Coon Lab developed a meta-scale approach to quantifying the human proteome and the massive number of protein variants produced by the human body. Proteomics is a cornerstone of biology and a precursor to understanding how protein dysfunction contributes to disease.

Mass spec fueling new explorations at the Carbone Cancer Center

Every cell has about 20,000 proteins, several hundred metabolites, and couple of thousand lipids. When those things get perturbed, bad things can happen. But measuring those changes may offer essential clues for fighting cancer.

Technical tour de force: Orphan proteins in mitochondrial disease

In new findings in Nature, a team at the Morgridge Institute for Research and Washington University School of Medicine in St. Louis analyzed dozens of ‘orphan’ mitochondrial proteins and suggested functions for many of them — an important step to finding better ways to diagnose and treat poorly understood human conditions.

Congratulations to May 2022 graduates

Congratulations to our 2022 graduating students and research staff moving on into their next chapters. A few of them shared their experiences at Morgridge and their plans for the future.

Game-changer: New tech could transform biotechnology

In new research in Nature Communications, the Joshua Coon Lab describes a game-changing advance that unites the power of mass spectrometry with the potential of electron microscopy (EM) — a finding that could transform biotechnology.

Morgridge, UW alum ‘diving into the deep end’ of vaccine development

After years of sharpening her knowledge of mass spectrometry in the Josh Coon Lab, chemistry PhD alumna Anji Trujillo landed her dream job of working on the front lines of drug development at Pfizer in St. Louis.

Open wide: Detecting links between what’s in your mouth and illness

Using tiny specks of dental plaque, scientists at the Morgridge Institute for the first time compiled a sophisticated analysis that opens the door to using the trove of micro-organisms in your mouth as an indicator of other health issues.

Where are they now? Catching up with recent alumni in their new careers

A few of our recent Morgridge alumni reflect on how their research experience at the institute prepared them for their scientific careers.

Coon lab’s ’smart toilets’ project a hot commodity

via The Wall Street Journal

Morgridge investigator Josh Coon’s unique project marrying mass spectrometry technology to the everyday toilet is tabbed as one of the trends to watch in the Wall Street Journal’s “Future of Everything” series.

‘Molecular Signature’ In Blood May Indicate Coronavirus Disease Severity

via Forbes

Researchers at the Morgridge Institute for Research, Albany Medical Center, and UW–Madison assembled a profile of biological molecules that correlated not only with COVID-19 infection, but with disease severity. More target molecules will likely be found as others analyze the data, which is freely available online.

Seize the Moment: Adapting old tools for a novel coronavirus

Morgridge scientists John Brubacher, Anthony Gitter, Brian Bockelman, Ben Cox and Katie Overmyer, joined Gabriella Gerhardt on July 22 for a Fearless Science webinar about rapidly applying technology and methods to answer COVID-19 questions.

Smart toilets could transform health tracking. Here’s how

via ZDNet

Morgridge investigator Josh Coon describes how “smart toilets” could be the new frontier in personalized medicine.

Albany Med Pulmonologist Partners with University of Wisconsin on COVID-19 Research

via Albany Medical College

An Albany Med physician who has been caring for COVID-19 patients during the pandemic is partnering with the Morgridge Institute and UW–Madison to study why some patients experience COVID-19 more severely than others.