The Cantor lab is jointly affiliated with the Metabolism Theme at the Morgridge Institute for Research and the Departments of Biochemistry and Biomedical Engineering at the University of Wisconsin-Madison.

Our lab has broad interests in modeling and understanding the influence of environmental factors on human cell metabolism, with a particular focus on hematological cancers and normal lymphocytes. We apply a highly interdisciplinary approach that combines principles of biochemistry, engineering, and molecular biology with methods in metabolomics, genome editing, and chemical genetics. Within this framework, we also integrate and develop novel tools and reagents, including a physiologic cell culture medium. Ultimately, we hope to exploit our findings for translation into new therapeutic opportunities.

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Principal Investigator Jason Cantor

Jason earned his B.S. in Chemical Engineering (2004) magna cum laude from Cornell University, and then completed his Ph.D. in Chemical Engineering (2010) from the University of Texas at Austin. Under the guidance of George Georgiou, Jason’s doctoral research focused on the development of new strategies to engineer therapeutic enzymes with reduced immunogenicity for cancer therapy, and was supported, in part, through a graduate fellowship awarded by the U.S. Department of Homeland Security. Jason then carried out his postdoctoral research in the laboratory of David M. Sabatini at the Whitehead Institute for Biomedical Research (MIT). There, he focused on designing new tools to better understand how environmental factors influence the metabolic regulation of cancer cells. His postdoctoral research was funded, in part, through fellowships awarded by both the American Cancer Society and the Koch Institute for Integrative Cancer Research at MIT, and was also later recognized with a Margaret and Herman Sokol Postdoctoral Award from the Whitehead Institute. In August 2018, Jason became a Metabolism Investigator at the Morgridge Institute for Research and an Assistant Professor in the Departments of Biochemistry and Biomedical Engineering at the University of Wisconsin-Madison.

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