When cells infected with HIV make contact with uninfected cells, a new study reveals how that connection unleashes a hornet’s nest of activity that helps drive transmission.
Category: Virology
Viral Copy Machine Revealed
GROW Magazine, a research publication for the UW–Madison College of Agricultural and Life Sciences, highlighted the research of Morgridge Investigator Paul Ahlquist on how viruses replicate their genomes within cells.
Cryo-EM studies reveal the ‘high-wire act’ of bacterial replication
Genome replication in bacteria frequently breaks down. Scientists at UW–Madison and Morgridge used Cryo-EM to precisely detail how bacterial proteins act like emergency first responders, repairing broken DNA on the fly.
Stunningly detailed blueprint revealed of viral genome replication machinery
Morgridge virologists have outlined in atomic detail the intricate RNA replication machines that coronaviruses create inside infected cells, giving rise to potential new strategies to fight disease.
From ‘blobology’ to atomic precision: Wisconsin’s leadership on cryo-EM imaging
Wisconsin is now an established national leader in cryo-electron microscopy, or cryo-EM, thanks to a decade-long strategic push from the UW–Madison biochemistry department and the Morgridge Institute.