Morgridge Institute Investigator Melissa Skala heralded the importance of the federal investment in scientific research during the annual “UW Day” on April 6 in Washington, D.C.
Morgridge Investigators Jason Cantor, Kevin Eliceiri, and Melissa Skala received award funding to advance projects in metabolism and biomedical imaging.
Morgridge investigator Melissa Skala has landed a grant from the National Eye Institute to develop a new imaging method that could allow for earlier disease detection, monitoring and treatment evaluation for retinal diseases.
An advanced biomedical imaging technique reveals how cancer cells can hijack the metabolic activity of certain non-cancer cells in the pancreas to fuel tumor growth.
A few of our recent Morgridge alumni reflect on how their research experience at the institute prepared them for their scientific careers.
Morgridge researchers developed an imaging technique that can predict the efficiency of cardiac muscle cell differentiation from stem cells as a method of quality control for potential regenerative therapies.
The Summer Science Workshop Series kicks off June 23 with 106 students and 29 educators from 21 schools in the Wisconsin Rural Schools Alliance and seven sites in the Upward Bound program that focuses on underrepresented and first-generation pre-college students.
Congratulations to our 2021 graduating students and research staff moving on into their next chapters. A few of them shared their experiences at Morgridge and their plans for the future.
Neuroendocrine cancers grow so slowly they often evade detection before it’s too late. By mimicking that slow growth in the lab, the Melissa Skala Lab hopes to speed up the creation of more effective treatments.
For more than ten years, the Field Trip Program has brought students and teachers to Madison for a day of activity and exploration. But when the COVID-19 pandemic shuttered on-campus activity, the Discovery Outreach Team had to get creative.
A few of our Morgridge alumni shared thoughts on their research experience at the Morgridge Institute, their plans moving forward and their warm shoutouts to some of the people who helped them along the way.
Medical Engineering graduate student Amani Gillette has become one of the Morgridge Institute’s top ambassadors for science outreach.
Researchers at the Morgridge Institute and UW-Madison want to ensure that pancreatic cancer treatment options are accessible to all — regardless of race, ethnicity, or insurance status — so that patients can make the most informed decisions regarding their care.
With every heartbeat comes a rhythmic pulse that helps blood flow through the body. Understanding this pulsatile flow can offer insights on the impacts of blood vessel development and cardiovascular disease. New research uses an “organ-on-a-chip” model to study pulsatile flow in a more biologically relevant way.
Morgridge Postdoctoral Fellow Jose Ayuso won the “Best Paper Award” at the 2020 Micro Total Analysis Systems conference for his work on cancer microenvironments in tumor evolution and progression.
A Morgridge imaging study of macrophages — immune cells that are important to human health, but paradoxically can help some cancers grow and spread — is offering better ways to understand these cells and target them with immunotherapies.
Researchers at the Morgridge Institute and UW-Madison have developed a novel label-free imaging technique that exploits autofluorescence in cells to differentiate between active and off-duty T cells.
A new imaging method developed by the Skala lab uses the natural autofluorescence within cells to assess T cell activity. The technique could help assess T cell involvement in immunotherapies.
Melissa Skala, a University of Wisconsin-Madison associate professor of biomedical engineering, and collaborators have used an approach called optical metabolic imaging (OMI) to effectively assess that heterogeneity and related treatment responses in organoids created with tissues from patients with breast cancer and pancreatic cancer.
Congratulations to the graduating students and research staff as they move onward and upward. A few of these students and staff shared about their time at the Morgridge Institute, their accomplishments and their plans for what’s next.
via Massive Science
Morgridge investigator Melissa Skala shares her perspective on a promising new approach to treating pancreatic cancer in this feature from Massive Science.
Peter Favreau, a postdoctoral researcher at the Morgridge Institute for Research, discusses how the use of Optical Microscopy is helping to create individualized effective cancer treatments based on each patient’s tumor cells.
Tom Still, president of the Wisconsin Technology Council, focused his statewide business column on July 21 on a novel eye research partnership between the Morgridge Institute and Medical College of Wisconsin.
The Morgridge Rural Summer Science Camp, where rural high school students and teachers take a deep dive into science research over the course of a week, is expanding and offering a third week of camp thanks to new support from a National Science Foundation (NSF) project.
A Madison-Milwaukee scientific partnership is powering an effort to better understand the complicated mechanics of human vision.
Conferences are Important for High School Students—Youth Apprentices and STEM Professional Development
Isabel Jones, Verona Area High School senior and second year YA, who works at the Morgridge Institute for Research, presented a scientific poster at one conference and spoke on a panel at another.
Imagine your chances of developing an invasive cancer were the same as a coin toss. Do you opt for aggressive treatments like surgery and chemotherapy, or do you take your chances that the cancer will never manifest?
Alexandra Walsh, an assistant scientist in the lab of Morgridge medical engineer Melissa Skala, is leading a project to use non-invasive fluorescence imaging to identify and sort T cells for use in cancer immunotherapy treatments. The technology won a 2018 Innovation Award from the Wisconsin Alumni Research Foundation.
Preterm births — which can lead to infant death or disability — are on the rise, accounting for nearly 400,000 of the country’s 4 million annual births. But doctors have a hard time figuring out which pregnant women are likely to deliver early.
As gene editing therapies for macular degeneration and other visual disorders work their way into clinical trials, the University of Wisconsin–Madison is on the forefront of research into making sure they are safe and effective.
Of the approximately 4 million births in the United States each year, at least 400,000 of them still trigger a state of desperation in maternity wards. Parents, doctors and medical staff feel this way over the challenge of managing high-risk pregnancies.
Three scientists at the Morgridge Institute for Research will describe what brought them to Madison and how breakthroughs in medical engineering, regenerative biology and medical imaging will help save lives at the Tuesday, Sept. 25 Tech Council Innovation Network luncheon meeting in Madison.
Melissa Skala and Paul Campagnola, a professor of biomedical engineering at UW-Madison, hope to make inroads toward improved drug therapies through a two-year National Institutes of Health Exploratory/Developmental Research Grant.
The study will use optical imaging techniques developed by Melissa Skala, a co-investigator at the Morgridge Institute, to monitor the evolution of 3D cancer tumor cultures over time.
With the semester winding down, we are thrilled to congratulate graduating students and research staff who are moving on and up. More than 110 undergraduate and graduate students, in addition to post-doctoral fellows, work across six biomedical research themes at the Morgridge Institute.
When Ava VanDommelen was seven, she asked for her first microscope for Christmas. Now, at 17-years-old, she’s using microscopy to explore cancer tumors and the immune system at the Morgridge Institute for Research.
Melissa Skala, a Morgridge Institute for Research investigator in medical engineering, won a highly competitive award from the nonprofit organization Stand Up to Cancer at its annual 2017 summit January in Santa Monica.
If there were two words that described Jose Dominguez they would be: radiating enthusiasm. It’s easy to see his incredible passion and positivity for his research and life.
By partnering with the Morgridge Institute for Research, BME landed internationally recognized optical imaging pioneers Melissa Skala and Jan Huisken to their new faculty ranks.
Oncologists are struggling to improve the grim survival rates of pancreatic cancer, which are especially frustrating in an era that is making good progress on other cancer fronts. “I think
Skala’s research problems focus on cancer detection and treatment, and her expertise in light-based, optical imaging is giving clinicians revolutionary new tools for the fight. Skala will be bringing her talents this summer from Vanderbilt University to the Morgridge Institute for Research and the University of Wisconsin-Madison, as a Morgridge investigator and professor of Biomedical Engineering (BME).
Scientific imaging has long been a research strength at the University of Wisconsin-Madison, home of major advances in cellular-scale optical imaging, human-scale medical imaging and many spaces in between.